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Research Article December 8 2023
TLR9 plus STING Agonist Adjuvant Combination Induces Potent Neopeptide T Cell Immunity and Improves Immune Checkpoint Blockade Efficacy in a Tumor Model
Melisa D. Castro Eiro; Kou Hioki; Ling Li; Merel E. P. Wilmsen; Caoimhe H. Kiernan; Inge Brouwers-Haspels; Marjan van Meurs; Manzhi Zhao; Harm de Wit; Dwin G. B. Grashof; Harmen J. G. van de Werken; Yvonne M. Mueller; Christopher Schliehe; Burcu Temizoz; Kouji Kobiyama; Ken J. Ishii; Peter D. Katsikis
J Immunol ji2300038.
Research Article December 6 2023
The Teleost CXCL13–CXCR5 Axis Induces Inflammatory Cytokine Expression through the Akt–NF-κB, p38–AP-1, and p38–NF-κB Pathways
J Immunol ji2300237.
Research Article December 6 2023
The UAF1–USP1 Deubiquitinase Complex Stabilizes cGAS and Facilitates Antiviral Responses
Zhongxia Yu; Li Tong; Chenkai Ma; Hui Song; Jie Wang; Li Chai; Caiwei Wang; Mengge Wang; Chunying Wang; Rongzhen Yan; Yue Fu; Mutian Jia; Wei Zhao; Chunyuan Zhao
J Immunol ji2200462.
Research Article December 6 2023
Mouse Trophoblast Cells Have Attenuated Responses to TNF-α and IFN-γ and Can Avoid Synergic Cytotoxicity of the Two Cytokines
J Immunol ji2300210.
Research Article December 4 2023
Inflammasome Activation and IL-1β Release Triggered by Nanosecond Pulsed Electric Fields in Murine Innate Immune Cells and Skin
Flavia Mazzarda; Alexandra E. Chittams-Miles; Julia Pittaluga; Esin B. Sözer; P. Thomas Vernier; Claudia Muratori
J Immunol ji2200881.
Research Article December 4 2023
Cytomegalovirus Infection Facilitates the Costimulation of CD57+CD28− CD8 T Cells in HIV Infection and Atherosclerosis via the CD2–LFA-3 Axis
Nicole E. Winchester; Soumya Panigrahi; Anokhi Haria; Archeesha Chakraborty; Xi Su; Bonnie Chen; Stephen R. Morris; Brian M. Clagett; Steven M. Juchnowski; Raghavendra Yadavalli; Francois Villinger; Mirko Paiardini; Karem Harth; Vikram S. Kashyap; Leonard H. Calabrese; Leonid Margolis; Scott F. Sieg; Carey L. Shive; Sara Gianella; Nicholas T. Funderburg; David A. Zidar; Michael M. Lederman; Michael L. Freeman
J Immunol ji2300267.
Research Article December 1 2023
HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice
Jeremy J. Racine; Adel Misherghi; Jennifer R. Dwyer; Richard Maser; Elvira Forte; Olivia Bedard; Susanne Sattler; Alberto Pugliese; Laurie Landry; Colleen Elso; Maki Nakayama; Stuart Mannering; Nadia Rosenthal; David V. Serreze
J Immunol ji2300303.
Research Article December 1 2023
CD8+ T Cell–Dependent Antitumor Activity In Vivo of a Mass Spectrometry–Identified Neoepitope despite Undetectable CD8+ Immunogenicity In Vitro
Marc A. Gillig; Cory A. Brennick; Mariam M. George; Jeremy L. Balsbaugh; Tatiana V. Shcheglova; Ion I. Mandoiu; Tatiana Rosales; Brian M. Baker; Pramod K. Srivastava; Sukrut H. Karandikar
J Immunol ji2300356.
Research Article December 1 2023
Antimicrobial Protein LECT2-b Helps Maintain Gut Microbiota Homeostasis via Selectively Targeting Certain Pathogenic Bacteria
J Immunol ji2300180.
Research Article December 1 2023
Cutting Edge: STING Induces ACLY Activation and Metabolic Adaptations in Human Macrophages through TBK1
Maximilian Nickenig; Matthew S. J. Mangan; Hye Eun Lee; Konstantinos Symeonidis; Antonia Henne; Romina Kaiser; Eike Geißmar; Hendrikus Garritsen; Zeinab Abdullah; Karsten Hiller; Eicke Latz; Mario A. Lauterbach
J Immunol ji2200835.
Research Article November 29 2023
Global Transcriptome Analysis Reveals Distinct Phases of the Endothelial Response to TNF
Eike C. Struck; Tatiana Belova; Ping-Han Hsieh; Jacob O. Odeberg; Marieke L. Kuijjer; Philip J. Dusart; Lynn M. Butler
J Immunol ji2300419.
Research Article November 29 2023
The Microbial Tryptophan Metabolite Contributes to the Remission of Salmonella typhimurium Infection in Mice
Yingying Li; Junqi Li; Dan Jia; Shandian Gao; Yanan Guo; Junlong Liu; Jinming Wang; Guiquan Guan; Jianxun Luo; Hong Yin; Sa Xiao; Youquan Li
J Immunol ji2300090.
Research Article November 29 2023
IL-17A Orchestrates Reactive Oxygen Species/HIF1α–Mediated Metabolic Reprogramming in Psoriasis
Bhavuk Dhamija; Soumitra Marathe; Vinanti Sawant; Moumita Basu; Diksha Attrish; Ditipriya Mukherjee; Sushant Kumar; Medha Gayathri J. Pai; Siddhi Wad; Abhijeet Sawant; Chitra Nayak; Kareenhalli V. Venkatesh; Sanjeeva Srivastava; Steven R. Barthel; Rahul Purwar
J Immunol ji2300319.
Research Article November 29 2023
Conditional NKT Cell Depletion in Mice Reveals a Negative Feedback Loop That Regulates CTL Cross-Priming
Christoph Heuser-Loy; Ann-Kathrin Baumgart; Carl-Philipp Hackstein; Christina J. F. Courrèges; Marie-Sophie Philipp; Christoph A. Thaiss; Tristan Holland; César Evaristo; Natalio Garbi; Christian Kurts
J Immunol ji2300662.
Research Article November 22 2023
Analysis of Butyrophilin-Mediated Activation of γδ T Cells from Human Spleen
Chunyan Wang; Anne Y. Lai; Dana C. Baiu; Kelsey A. Smith; Jon S. Odorico; Keith Wilson; Taylor Schreiber; Suresh de Silva; Jenny E. Gumperz
J Immunol ji2300588.
Research Article November 22 2023
4-Octyl Itaconate Alleviates Airway Eosinophilic Inflammation by Suppressing Chemokines and Eosinophil Development
Maureen Yin; Ridhima Wadhwa; Jacqueline E. Marshall; Caitlin M. Gillis; Richard Y. Kim; Kamal Dua; Eva M. Palsson-McDermott; Padraic G. Fallon; Philip M. Hansbro; Luke A. J. O’Neill
J Immunol ji2300155.
Research Article November 20 2023
Both Humoral and Cellular Immunity Limit the Ability of Live Attenuated Influenza Vaccines to Promote T Cell Responses
J Immunol ji2300343.
Research Article November 20 2023
STAT3 Deficiency Alters the Macrophage Activation Pattern and Enhances Matrix Metalloproteinase 9 Expression during Staphylococcal Pneumonia
Susan Farmand; Vicky Sender; Jens Karlsson; Padryk Merkl; Staffan Normark; Birgitta Henriques-Normark
J Immunol ji2300151.
Research Article November 20 2023
Establishment of CD8+ T Cell Thymic Central Tolerance to Tissue-Restricted Antigen Requires PD-1
Julia F. May; Rees G. Kelly; Alexander Y. W. Suen; Jeongbee Kim; Jeongwoo Kim; Colin C. Anderson; Gina R. Rayat; Troy A. Baldwin
J Immunol ji2200775.
Research Article November 17 2023
Single-Cell Transcriptional Analysis of Lamina Propria Lymphocytes in the Jejunum Reveals Innate Lymphoid Cell–like Cells in Pigs
Junhong Wang; Ming Gao; Mingyang Cheng; Jiawei Luo; Mei Lu; Xinyuan Xing; Yu Sun; Yiyuan Lu; Xiaoxu Li; Chunwei Shi; Jianzhong Wang; Nan Wang; Wentao Yang; Yanlong Jiang; Haibin Huang; Guilian Yang; Yan Zeng; Chunfeng Wang; Xin Cao
J Immunol ji2300463.
Research Article November 17 2023
Distinct Functional Humoral Immune Responses Are Induced after Live Attenuated and Inactivated Seasonal Influenza Vaccination
Xin Tong; Yixiang Deng; Deniz Cizmeci; Laura Fontana; Michael A. Carlock; Hannah B. Hanley; Ryan P. McNamara; Daniel Lingwood; Ted M. Ross; Galit Alter
J Immunol ji2200956.
Research Article November 15 2023
The Proteasome Inhibitor Bortezomib Induces p53-Dependent Apoptosis in Activated B Cells
J Immunol ji2300212.
Research Article November 13 2023
Human Intestinal Dendritic Cells Can Overcome Retinoic Acid Signaling to Generate Proinflammatory CD4 T Cells with Both Gut and Skin Homing Properties
Hannah Gordon; Katherine Wichmann; Amy Lewis; Theodore Sanders; Martha Wildemann; Inva Hoti; Eve Hornsby; K. Bel Kok; Andrew Silver; James O. Lindsay; Andrew J. Stagg
J Immunol ji2300340.
Research Article November 13 2023
Plasma Cell Differentiation, Antibody Quality, and Initial Germinal Center B Cell Population Depend on Glucose Influx Rate
Shawna K. Brookens; Sung Hoon Cho; Yeeun Paik; Kaylor Meyer; Ariel L. Raybuck; Chloe Park; Dalton L. Greenwood; Jeffrey C. Rathmell; Mark R. Boothby
J Immunol ji2200756.
Research Article November 8 2023
Forodesine Enhances Immune Responses through Guanosine-Mediated TLR7 Activation while Preventing Graft-versus-Host Disease
Takashi Ikeda; Kazuya Sato; Shin-ichiro Kawaguchi; Junko Izawa; Norihito Takayama; Hiroko Hayakawa; Kento Umino; Kaoru Morita; Kana Matsumoto; Kentaro Ushijima; Yoshinobu Kanda
J Immunol ji2300003.
